The wrong suspect?

The wrong suspect?

P atients with Parkinson's disease (PD) suffer a specifi c loss of dop-aminergic neurons from the mid-brain region that controls motor function. The exact mechanism of this selective neurodegeneration is unclear, though many lines of evidence point to dysfunctional mitochondrial complex I as one root cause of the disease. Yet Choi et al. now suggest that defective regulation of micro-tubules ma...

Prime suspect.

Background: Human T-lymphotropic virus type-1 (HTLV-1) causes adult T-cell leukemia/ lymphoma and is linked to a number of lymphocyte-mediated disorders. HTLV-1 contains both regulatory and accessory genes in four pX open reading frames. pX ORF-II encodes two proteins, p13 and p30, whose roles are still being defined in the virus life cycle and in HTLV-1 virus-host cell interactions. Proviral c...

Glaucoma Suspect

Glaucoma suspect describes a person with one or more risk factors that may lead to glaucoma, but this individual does not have definite glaucomatous optic nerve damage or visual field defect. The number of individuals with eye findings that raise a suspicion of glaucoma, usually elevated intraocular pressure (IOP) or asymmetric optic disk morphology, far exceeds the number of people who have be...

Suspect cubic diamond "impact" proxy and a suspect lonsdaleite identification.

Technology and the Glaucoma Suspect.

PURPOSE To determine and compare the diagnostic performance of spectral-domain optical coherence tomography (SD-OCT), stereoscopic disc photographs, and automated perimetry as assessed by a group of glaucoma specialists in differentiating individuals with early glaucoma from suspects. METHODS Forty-six eyes (46 patients) with suspicious optic nerves had previously undergone SD-OCT scans, 24-2...